Triclinic Labs installs and now offers Variable Temperature – Variable Relative Humidity Powder X-ray Diffraction (PXRD)
X-ray diffraction patterns of theophylline monohydrate (Theo-FM) held at 5% rH collected between 5 ˚C and 83 ˚C. Conversion from the monohydrate to a metastable form occurs (Theo-Meta). At 55 ˚C the Theo-FM disappears. Theophylline Form II (Theo-F2) appears at 40 ˚C.
The system offers temperature and humidity control for real time observation of structural changes in materials under non-ambient conditions using PXRD.
Steef Boerrigter, Ph.D. who leads the materials modeling group at Triclinic Labs stated: “This instrumentation combination enables in situ characterization under an incredibly wide range of working conditions you might encounter in development, manufacturing, and storage. When combined with differential scanning calorimetry, thermo-gravitational analysis, and/or dynamic vapor sorption analysis, it offers an incredibly deep understanding of phase transitions that are otherwise very difficult or impossible to observe. In addition to equilibration studies, scanning mode analysis offers a view of the rate and dynamics of the phase transitions.”
Often referred to as Variable Temperature – Variable Relative Humidity Powder X-ray Diffraction (VT/VRH/PXRD). This new addition supports investigations into pharmaceuticals, fine chemicals, and clays or zeolites in humid air, inert gasses, or vacuum. Due to its versatility, the new VT/VRH/PXRD setup opens new dimensions in analysis for materials science.
The VT/VRH/PXRD system at Triclinic Labs offers the following features:
• 2% to 95% relative humidity with variable temperature from 10 to 80 °C,
• −5 °C to +300 °C in air or dry nitrogen,
• −120 °C to +300 °C using liquid nitrogen cooling system,
• −180 °C to +400 °C using liquid nitrogen cooling system and vacuum,
• Atmospheres: vacuum (< 10−2 mbar), air, inert gasses,
• Reflection-geometry PXRD in 2θ range of 0°–164°,
• Data collection strategies include program-controlled VT/VRH points or continuous scanning modes.
For more information on how Triclinic Labs can assist with in-situ VT/VRH/PXRD sample analysis needs, please request a free consultation by clicking here. To contact Steef Boerrgter, you may email him at sboerrigter@tricliniclabs.com.
Steef Boerrigter, Ph.D.
Triclinic Labs, Inc.
sboerrigter@tricliniclabs.com
Visit us on social media:
LinkedIn
Distribution channels: Agriculture, Farming & Forestry Industry, Chemical Industry, Healthcare & Pharmaceuticals Industry, Science
Legal Disclaimer:
EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.
Submit your press release