Concentrations of Irinotecan and SN-38 in the Ascites and the Fluid Product of Cell-Free and Concentrated Ascites ...
Introduction Irinotecan (CPT-11), a camptothecin analog, has been evaluated as monotherapy and combination chemotherapy for various solid malignancies such as gastric, colorectal, lung, breast, and ovarian cancers.1 CPT-11 is a prodrug that requires …